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serial lactate septic shock. Publication � Serial measurement of arterial lactate concentrations as a prognostic indicator in relation to the 6 with severe sepsis, and 2 with septic shock. Severe Sepsis/Septic Shock Recognition and Treatment Protocols Subject 2. Serial lactate trending goal to achieve a 10 decrease from an In a recent study we found no difference in the concentrations of luminal lactate in the rectum between nonsurvivors and survivors in early septic shock ( 24 h). Table 3 Clinical subtypes of shock and aetiology, key signs, investigations and management Distributive shock Cardiogenic shock Hypovolaemic shock 178 BC MEDICAL JOURNAL VOL. 54 NO. 4, MAY 2012 www.bcmj.org These studies and an understand-ing of the cardiovascular pathophysi-ology of sepsis led Rivers to … Duration of Shock before Antibiotics • JID 2006 193 (15 January) • 257 Figure 6. Sequence of hemodynamic, cytokine, and lactate responses in untreated septic mice. Lactate as a Marker for Perfusion and use in Resuscitation Geoff Heffner, DVM Diplomate ACVECC Sunday, Sept 30, 2012 Abstract Purpose The prognostic value of hyperlactatemia in septic shock is unquestionable. However, as current definitions do not include hyperlactatemia as a

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